Statistical Methods in Health Disparities Research

In this section, we provide slides for presentations and lectures on a variety of statistical methods in health disparities research. Most are introductory and a few are more advanced.

Testing Mediators and Moderators (Interactions) of Outcomes: Resources

Mediation and moderation are integral methods for investigating health disparities in aging research. We provide several types of resources on these topics including presentations, slides, links to web pages, and PDF documents.

Mediation and Moderation

Mediation and Moderation 101: Tor Neilands (RCMAR Webinar, 2022) A broad overview of historical and current mediation and moderation analysis methods as of 2021. Introduces the concept of statistical mediation and three conceptual approaches to mediation analysis. A YouTube webinar recording, presentation slides, and a Q&A document are available.

Mediation

Introduction to mediation as a concept: David Kenny (2021) Introduces four steps of mediation, indirect effects, power, how to report results, and how to incorporate additional variables. Links to other sites with information on mediation, as well as to his mediation webinars.

Causal mediation analysis in Stata (2024) A webinar introducing basic principles of causal mediation with examples using Stata’s -mediation- command.

Conceptualizing and testing mediated effects: Steve Gregorich (2014) How to conceptualize, test, and interpret a variety of mediation models to explore mechanisms of health disparities.

Moderation

​​​​​Moderator variables - an introduction: David Kenny (2018) Overview of moderator variables and various situations (e.g., categorical moderators and causal variables) including links to his moderation webinars. 

Testing effect modification: Steve Gregorich (2014) Conceptualizing and testing moderated effects: introduces the concept of moderation in the context of exploring mechanisms of health disparities. 

Tidbits on exploring interaction effects in logistic regression analyses: Tor Neilands (2024)  Methods to decompose and interpret statistically significant interaction effects among categorical and continuous predictors in logistic regression analyses using Stata (with SAS resource links).​​​

Methods of Analyzing Longitudinal Datasets

 

Factor Analysis Methods

 

Additional Statistical Issues

 

  • Comparing Odds Ratios Across Nested Logistic Regression Models: Care must be taken when comparing odds ratios across two logistic regression models where the X variables in one model are a subset of the X variables in the other model (2013).
  • 3-level Logistic Models: Reviews SAS options circa 2013 for 3-level logistic models, including both multilevel models with random effects and alternating logistic regression (ALR) models.  NOTE: SAS now includes the FASTQUAD option in PROC GLIMMIX, which allows fitting models with larger numbers of random effects and quadrature points.
  • Missing Data Concepts: A no-math introduction to multiple imputation (2009).